Meeting Program 2017-08-30T18:57:46+00:00

Mixtures abstract book cover

Meeting Program

Download a copy of the abstract book (version 6).

Platform presentations will be held in the Four Square Ballroom.
Poster presentations, coffee breaks and poster socials will be held in the Marco Polo Ballroom.

Problem Formulation

Time Title Speakers
8:00 a.m.–8:30 a.m. Opening Remarks Eric Van Genderen and Mary Ann Ottinger, Program Committee Co-Chairs
8:30 a.m.–9:00 a.m. 1 Toxicological and Environmental Risk Assessment of Chemical Mixtures: A Critical Overview of Concepts, Methods and Approaches Thomas Backhaus
University of Gothenburg, Sweden
9:00 a.m.–9:30 a.m. 2 Mixture Toxicology in the 21st Century: Pathway-Based Concepts and Tools Gerald Ankley
USEPA, USA
9:30 a.m.–10:00 a.m. 3 A Brief Overview of Regulatory Frameworks and Approaches to the Ecological Assessment of Mixtures Karen Eisenreich
USEPA, USA
10:00 a.m.–10:30 a.m. Break
10:30 a.m.–11:00 a.m. 4 Troubling Mismatch Between Research on Compounds of Emerging Concern (CECs) and Societal Needs Gunilla Öberg
University of British Columbia, Canada

Exposure Assessment

Time Title Speakers
11:00 a.m.–11:30 a.m. 5 Identifying Complex Mixtures in the Environment With Cheminformatics and Non-targeted High-Resolution Mass Spectrometry Emma Schymanski
EAWAG, Switzerland
11:30 a.m.–12:00 p.m. 6 The Use of Non-Targeted Analysis (NTA) and Suspect Screening Analysis (SSA) for Human Exposure Assessment at the USEPA: Successes and Challenges Mark Strynar
USEPA, USA
12:00 p.m.–1:30 p.m. Break
1:30 p.m.–2:00 p.m. 7 Extensive Target-Chemical Analysis and Biological Assays Illustrate Mixed-Organic-Contaminant Exposure and Effects in USA Streams Paul Bradley
USGS, USA
2:00 p.m.–2:30 p.m. 8 Combined Exposure Assessment of 37 Substances From Mixed Land Use Catchments to Assess Prospective Aquatic Risk Christopher Holmes
Waterborne Environmental, USA
2:30 p.m.–3:00 p.m. 9 Assessing Chemical Mixture Exposures Using spatial Principle Components Analysis (sPCA) and Geospatial Methods Kristin Eccles
University of Ottawa, Canada
3:00 p.m.–3:30 p.m. Break
3:30 p.m.–4:00 p.m. 10 Species Sensitivity May Influence the Determination of Additivity in Metal–Mixture Toxicity Elizabeth Traudt
Colorado School of Mines, USA
4:00 p.m.–4:30 p.m. Facilitated Discussion Kevin Brix and Ed Furlong, Program Committee
4:30 p.m.–5:30 p.m. Poster Social

Effects Assessment

Time Title Speakers
8:00 a.m.–8:30 a.m. 11 The ADME of Toxicological Interactions and Mixtures Risk Assessment Moiz Mumtaz
Agency for Toxic Substances and Disease Registry, USA
8:30 a.m.–9:00 a.m. 12 Embracing Biological and Chemical Complexity Improves the Ecological Relevance of Effect Assessment Travis Schmidt
U.S. Geological Survey, USA
9:00 a.m.–9:30 a.m. 13 Mesocosm Experiments Conducted With Metal Mixtures Often Reveal Ecological Surprises William Clements
Colorado State University, USA
9:30 a.m.–10:00 a.m. 14 Integration of Chemical, Organismal, and Transcriptomic Data Reveals Landscape-specific Exposure Effects to Complex Chemical Mixtures David Bertolatus
University of Colorado
10:00 a.m.–10:30 a.m. Break
10:30 a.m.–11:00 a.m. 15 Mixture Toxicity Prediction via Quantitative Toxicogenomics-based Approach Na Gou
Northeastern University, USA
11:00 a.m.–11:30 a.m. 16 Toxicity Modeling With Parallel Factor (PARAFAC) Decomposition From the Perspective of Mixture Toxicity Prediction With Time Series Toxicogenomic Data Sheikh Rahman
Northeastern University, USA
11:30 a.m.–12:00 p.m. Facilitated Discussion Thomas Backhaus and Mark Johnson, Program Committee
12:00 p.m.–1:30 p.m. Break

Risk Assessment and Management

Time Title Speakers
1:30 p.m.–2:00 p.m. 17 An Evidence-based Tiered Risk Assessment Scheme for Metal Mixtures in Freshwater Ecosystems Karel A.C. De Schamphelaere
Ghent University, Belgium
2:00 p.m.–2:30 p.m. 18 Use of the Basic Hazard Index Mixtures Screening Method for Rapid Assessment Valerie Adams
U.S. Army Public Health Center, USA
2:30 p.m.–3:00 p.m. 19 Risk Assessment and Regulation of Chemical Mixtures – Plant Protection Products Mick Hamer
Syngenta, UK
3:00 p.m.–3:30 p.m. Break
3:30 p.m.–4:00 p.m. 20 Developing Management Strategies for Mixtures: A Path Forward Based on a Review of Cumulative Risk Assessment Nathalie Vallotton
Dow Europe GmbH, Switzerland
4:00 p.m.–4:30 p.m. 21 Assessing the Effects of Chemical Mixtures Using a Bayesian Network Relative Risk Model (BNRRM) Integrating Adverse Outcome Pathways (AOPs) Valerie Chu
Western Washington University, USA
4:30 p.m.–5:00 p.m. 22 Application of the MIXTOX Model in the Characterization of Neonicotinoid Mixture Toxicity to Chironomus dilutus Erin Maloney
University of Saskatchewan, Canada
5:00 p.m.–5:30 p.m. Facilitated Discussion  Amy Beasley and Kevin Brix, Program Committee
5:30 p.m.–6:30 p.m.  Poster Social

Case Studies

Time Title Speakers
8:30 a.m.–9:00 a.m. 23 Combining Chemical Analysis, Bioanalysis and Risk Assessment to Prioritize Risk Driving Substances in Wastewater-Impacted Streams Juliane Hollender
EAWAG, Switzerland
9:00 a.m.–9:30 a.m. 24 A Multipronged, Effects-Driven Exposure and Impact Assessment of Chemicals of Emerging Concern in Rivers of the Great Lakes Edward Perkins
US Army Engineer Research and Development Center, USA
9:30 a.m.–10:00 a.m. 25 Important Considerations for the Environmental Risk Assessment of Mixtures of Alkylphenol Ethoxylates and Their Degradation Products Katherine Coady
The Dow Chemical Company, USA
10:00 a.m.–10:30 a.m. Break
10:30 a.m.–11:00 p.m. 27 Mixtures Risk Assessment: Finding Opportunity Amidst Chaos Eric Van Genderen, International Zinc Association, USA
11:00 a.m.–12:00 p.m. Closing Discussion Eric Van Genderen, Mary Ann Ottinger and Thomas Backhaus, Program Committee

Posters displayed on Wednesday are marked WP, and posters displayed on Thursday are marked RP.

Problem Formulation

Title Speakers
WP001 GCxGC-based Property Estimation for Risk Assessment of Complex Petrochemical Mixture Including the Generated Compounds in the Engine Oils Yasuyuki Zushi
National Institute of Advanced Industrial Science and Technology, Japan
WP002 In the Mix – the Pitfalls of Assessing Mixtures for Regulatory Purposes Claire Phillips
Cefas Lowestoft Laboratory, United Kingdom

Exposure Assessment

WP003 Chemical and Biological Assessment of Endocrine Disrupting Chemicals in Wastewater and Coastal Waters in Kuwait Withdrawn Noura Al-Jandal
Kuwait Institut for Scientific Research, Kuwait
WP005 Challanges of Testing Chemical Mixtures in Aquatic Toxicology Studies Henry Krueger
Wildlife International, United States
WP006 Assessing Exposure of Bald Eagle Nestlings to Organochlorine Compounds in Michigan (2015–2017) and Voyageur’s National Park, Minnesota (2011–2017) Rachel Eberius
University of Maryland at College Park, United States
WP007 New Approach for Toxicity Assessment Avoiding the Chemical Reaction Between Target Metals and Culture Medium Contents Gissela Pascual
Tohoku University, Japan
WP008 Occupational Exposure of Butchers to Toxic Mixtures in Fumes From Burning Tyres Employed in De-Furring of Animals in Nigerian Abattoirs Francis Okonkwo
University of Nigeria, Nigeria
WP009 Trends of Known and New Contaminants of Emerging Concern Measured in a Wastewater-Influenced Stream Using Passive Samplers Edward Furlong
U.S. Geological Survey, United States
WP010 Unpredictable Effects on Target Gene Expression Evaluated in Zebrafish Exposed to Pharmaceutical Mixtures Gabriela Aguirre-Martinez
Arturo Prat University, Chile

Risk Assessment and Management

WP011 Risk Assessment Methods That Simplify Chemical Mixtures Associated With Treated Domestic Wastewater Discharges Jerome Diamond
Tetra Tech, Inc., United States
WP012 A Novel Methodology for Screening Hazard and Risk From Environmental Exposures to Mixtures Hans Plugge
3E Company, United States
WP013 A Web-Based Integrated Platform for Mixture Risk Assessment Tools Jongwoon Kim
KIST Europe, Germany
WP014 Ecological Risk Assessment of Barite (BaSO4) Using Ecotoxicological Tests With Twelve Non-target Organisms Christian Paredes
Instituto del Mar del Perú, Peru
WP015 Human Dietary Intake and Hazard Characterization for the Residues of Neonicotinoides and Organophosphorus Pesticides in Egyptian Honey Yahya Alnaggar
Saskatchewan University, Egypt
WP016 Incorporating the Joint Toxicity of Co-applied Pesticides into the Ecological Risk Assessment Process Jason Belden
Oklahoma State University, United States
WP017 Selenoenzymes as Molecular “Targets” of Irreversible Inhibition by Mercury, Cadmium, and Similarly Electrophilic Inorganic and Organic Neurotoxicants Nicholas Ralston
University of North Dakota, United States
WP018 Toxicity of Uranium Mining Contaminant Mixtures to Tropical Freshwater Species Melanie Trenfield
Environmental Research Institute of the Supervising Scientist, Australia
WP019 Assessing the Impacts of Toxic Mixtures Over a Broad Geographic Scale: Challenges and First Steps Withdrawn David Baldwin
NOAA Fisheries, United States

Effects Assessment

RP001 Integration of Chemical, Organismal, and Transcriptomic Data Reveals Landscape-Specific Exposure Effects to Complex Chemical Mixtures David Bertolatus
University of Colorado Denver, United States
RP002 Atmospheric Aging of Pesticides Mixtures Used to Control Mosquito Populations Sascha Usenko
Baylor University, United States
RP003 Combination of Linear Process Yields Non-linear Toxic Effect in Chemical Mixtures Masashi Kamo
Advanced Industrial Science and Technology, Japan
RP004 Gene Expression Profile in Thediatom T. pseudonana Upon Exposure to the Chemical  Mixtures at Environmental Concentrations. What Did We Learn? Teresa Lettieri
European Commission Joint Research Centre, Italy
RP005 Eco/Genotoxicity Assessment of Sediment Samples Under the Influence of a Submarine Outfall in Brazil Mariana Artal
University of São Paulo, Brazil
RP006 Transcriptomics Provides Mechanistic Indicators of Mixture Toxicology for IMX-101 and IMX-104 Formulations in Fathead Minnows Kurt Gust
US Army Engineer Research and Development Center, United States
RP007 Predicting Sediment Metal Toxicity to Hyalella azteca Using a Metals Mixtures Version of the Biotic Ligand Model Robert Santore
Windward Environmental, LLC, United States
RP008 Effects of the Discharge of Coalbed Methane Produced Water on Macroinvertebrate Stream Communities in the Bosquedel Oso State Wildlife Area, Colorado Keli Kringel
Colorado State University, United States
RP009 Evaluating Mixture Toxicity Using Two Aquatic Model Organisms and a Multi-tiered Approach David Pitts
Wayne State University, United States
RP010 Microbial Community Responses to Individual Metals and Metal Mixtures Brian Wolff
Colorado State University, United States
RP011 SynToxTool: Prediction of Synergistic Toxicity of Mixtures by Using Chemical-Protein and Protein-Protein Networks Jongwoon Kim
KIST Europe, Germany
RP012 The Synergistic Potential of Azole Fungicides in the Aquatic Invertebrate Gammarus pulex Juliane Hollender
Eawag, Swiss Federal Institute of Aquatic Science and Technology, Switzerland

Case Studies

RP013 Comparison of Macroinvertebrate Communities at Organic-Polluted River Sites With Different Zinc Concentrations: Is Single-Chemical Regulation Worth It? Yuichi Iwasaki
National Institute of Advanced Industrial Science and Technology (AIST), Japan
RP014 How Is the Tiered Framework of Mixtures Assessment Applicable to Regulatory Environmental Risk Assessment?  An Attempt Through Case Studies Kunihiko Yamazaki
Ministry of the Environment, Japan
RP015 MixToxDB Ver. 1.0: An Online Database on the Toxicity of Binary Chemical Mixtures to Environment-Living Organisms Jongwoon Kim
KIST Europe, Germany
RP016 Retrospective Application of “Concentration Addition” to Ni Toxicity Thresholds Determined for Field Studies in Soils with Elevated Co and Cu Beverley Hale
University of Guelph, Canada